Process for producing aziridine-2-carboxylic acid or its salts

C - Chemistry – Metallurgy – 07 – D

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260/337.5

C07D 203/06 (2006.01) C07D 203/08 (2006.01)

Patent

CA 1161854

Title of the Invention PROCESS FOR PRODUCING AZIRIDINE-2- CARBOXYLIC ACID OR ITS SALTS Abstract of the Disclosure A process for producing aziridine-2-carboxylic acid or its salts is provided which comprises treating an alpha-halogeno-beta-aminopropionitrile or its mineral acid salt with an alkali or alkaline earth metal hydroxide in water or in a water-containing organic solvent. In a preferred embodiment, aziridine-2-carboxylic acid or its salt is produced by treating the reaction mixture containing an alpha-halogeno-beta-aminopropionitrile obtained by reacting an alpha,beta-dihalogenopropionitrile or an alpha- halogenoacrylonitrile with ammonia, with an alkali or alkaline earth metal hydroxide in the presence of water without isolating the alpha-halogeno- beta-aminopropionitrile from the reaction mixture beforehand.

366597

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