Process for producing isatoic anhydrides

Details Process for producing isatoic anhydrides Process for producing isatoic anhydrides

C - Chemistry, Metallurgy

07

D

C07D 265/26 (2006.01) C07D 413/02 (2006.01)

Patent

CA 2193932

A process for producing isatoic anhydrides of the formula (II): (see fig. I) (II) which comprises reacting an anthranilic acid of formula (see fig II) (I) or a salt thereof with phosgene using a mixed solvent of water and an organic solvent miscible with water and inert to the reaction; conducting the reaction in the coexistence of an alkylpyridinium salt in an aqueous solvent; or using a mixed solvent of water and a specific amount of an organic solvent substantially immiscible with water and inert to the reaction.

Procédé de production d'anhydrides isatoïques de formule (II) : (voir fig. I) (II) qui consiste à faire réagir un acide anthranilique de formule (voir fig II) (I) ou un sel de ce dernier avec un solvant organique miscible dans l'eau et inerte dans cette réaction; à réaliser la réaction en présence d'un sel d'alkylpyridinium dans un solvant aqueux; ou à utiliser un solvant mixte composé d'eau et d'une quantité spécifique d'un solvant organique substantiellement non miscible dans l'eau et inerte dans cette réaction.

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