Process for producing novel penicillins and cephalosporins

C - Chemistry – Metallurgy – 07 – D

Patent

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260/104.3, 260/1

C07D 499/70 (2006.01) C07D 499/00 (2006.01) C07D 501/20 (2006.01)

Patent

CA 1077925

ABSTRACT OF THE DISCLOSURE A process for producing a novel penicillin and cephalosporin which contain a monooxo- or dioxo- piperazino-(thio)carbonylamino group in molecule and which are valuable anti-bacterial compounds for use in mammals including man, by reacting an imino ether compound having a .beta.-lactam ring with a reactive derivative in the carboxyl group of an amino acid having a mono- or di-oxo-piperazino carbonyl group, thereafter hydrolyzing the resulting reaction product and, if necessary, removing the protecting group.

260041

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