C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 227/16 (2006.01) C07C 231/00 (2006.01) C07C 229/52 (2006.01) C07C 229/62 (2006.01) C07C 237/46 (2006.01)
Patent
CA 2759342
The present invention relates to a process for the preparation of iodinated anilines; in particular, it relates to a process including the direct iodination, with suitably activated iodine, of 3,5- disubstituted anilines to the corresponding 3,5-disubstituted-2,4,6-triiodoanilines, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
La présente invention porte sur un procédé pour la préparation d'anilines iodées ; en particulier, elle porte sur un procédé comprenant l'iodation directe, avec de l'iode activé de façon appropriée, d'anilines 3,5-disubstituées en les 2,4,6-triiodoanilines 3,5-disubstituées correspondantes, qui sont des intermédiaires utiles pour la synthèse de produits de contraste pour les rayons X, et sur la préparation des produits de contraste eux-mêmes.
Citterio Attilio
Ferrigato Aurelia
Fretta Roberta
Lattuada Luciano
Leonardi Gabriella
Bracco Imaging S.p.a.
Smart & Biggar
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