Process for the preparation of...

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C - Chemistry, Metallurgy

07

C

C07C 59/88 (2006.01) C07C 51/353 (2006.01) C07C 51/373 (2006.01)

Patent

CA 2279637

Process for the preparation of 4-(4'-chlorobiphenyl-4-yl)-4-keto-2- methylenebutyric acid The invention relates to a process for the preparation of 4-(4'-chlorobiphenyl- 4-yl)- 4-keto-2-methylenebutyric acid of the formula (I) by Friedel-Crafts acylation of 4-chlorobiphenyl with itaconic anhydride, which comprises carrying out the Friedel-Crafts acylation in aromatic solvents at a temperature from -20 to +80°C.

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