C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/506 (2006.01)
Patent
CA 2729703
The present invention is directed to processes for the preparation of benzoimidazol-2-yl pyrimidine derivatives useful as histamine H4 receptor modulators, and a crystalline hemi-tartrate of [5-(4,6-dimethyl-1H-benzoimidazol-2-yl)-4-methyl- pyrimidin-2-yl]-[3-(1-methyl-piperidin-4-yl)-propyl]-amine.
La présente invention concerne des dérivés de benzoimidazol-2-yl-pyrimidine utiles en tant que modulateurs des récepteurs de lhistamine H4 ainsi que des procédés de préparation de tels composés.
Broggini Diego
Cesco-Cancian Sergio
Grimm Jeffrey S.
Lochner Susanne
Mani Neelakandha S.
Janssen Pharmaceutica Nv
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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