Process for the preparation of benzoimidazol-2-yl pyrimidine...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/04 (2006.01) A61K 31/506 (2006.01)

Patent

CA 2729703

The present invention is directed to processes for the preparation of benzoimidazol-2-yl pyrimidine derivatives useful as histamine H4 receptor modulators, and a crystalline hemi-tartrate of [5-(4,6-dimethyl-1H-benzoimidazol-2-yl)-4-methyl- pyrimidin-2-yl]-[3-(1-methyl-piperidin-4-yl)-propyl]-amine.

La présente invention concerne des dérivés de benzoimidazol-2-yl-pyrimidine utiles en tant que modulateurs des récepteurs de lhistamine H4 ainsi que des procédés de préparation de tels composés.

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