Process for the preparation of epibatidine

Details Process for the preparation of epibatidine Process for the preparation of epibatidine

C - Chemistry, Metallurgy

07

D

C07D 487/08 (2006.01)

Patent

CA 2137613

The invention relates to a process for the preparation of racemic or optically active epibatidine of the Formula XIV Image (XIV) which comprises subjecting racemic or optically active epi-epibatidine of the Formula XIII Image (XIII) to epimerization in the presence of a base. The advantage of the process is that readily available starting materials are used and the procedure is suitable for industrial scale productions too. Epibatidine is a known highly affective analgesic active ingredient.

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