Process for the preparation of hydroxylamine ethers and...

C - Chemistry – Metallurgy – 07 – C

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C07C 239/20 (2006.01) C07C 251/54 (2006.01) C07C 255/64 (2006.01) C07C 259/06 (2006.01)

Patent

CA 2151817

In order to prepare hydroxylamino-ethers having formula (I), in which X stands for NO2, CN. halogen. alkyl and halogen alkyl: Y stands for H, NO2. CN, halogen, alkyl and halogen alkyl: n equals 0 to 2 or 1 w 4 when Y and all X's sand for halogen: alk stands for possibly substituted alkylene, as well as their salts with mineral acids or strong organic acids, either a hydroxyimino compound having formula (II) in which R1 stands for alkyl, R2 stands for alkyl, alkoxy or R1 + R2 stand for an alkylene chain, is reacted in the presence of an alkali metal hydroxide, alkali metal alcoholate, alkali metal hydrogen carbonate or alkali metal carbonate as bases, or the corresponding anion of (II) is directly reacted with an alkylating agent having formula (III], in which R3 stands for possibly substituted alkyl or phenyl. so that an oximino derivate having formula (IV) is produced. The oximino derivative (IV) is split by a mineral acid or a strong organic acid into a salt of (I), and if desired the latter is converged into the free compound (I) by means of a base. The hydroxylamino-ethers (I) constitute intermediate products for plant protecting and pharmaceutical agents.

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