Process for the production of a low molecular weight heparin

Details Process for the production of a low molecular weight heparin Process for the production of a low molecular weight heparin

C - Chemistry, Metallurgy

08

B

C08B 37/10 (2006.01)

Patent

CA 2608136

The invention provides a process for the production of a very low molecular weight heparin (VLMWH) composition having a VLMWH content, relative to total heparin content, of at least 10% wt, said process comprising chromatographically or chemically or by filtration reducing the relative proportion of heparin having a molecular weight above 8000Da in a heparin composition extracted from a non-mammalian, vascularised marine animal.

La présente invention propose un procédé de production d'une composition d'héparine à très faible masse moléculaire (Very Low Molecular Weight Heparin ; VLMWH) ayant une teneur en VLMWH d'au moins 10 % en masse par rapport à la teneur totale en héparine. Ledit procédé comprend la réduction, par des moyens chromatographiques ou chimiques ou par filtration, de la proportion relative de l'héparine de masse moléculaire supérieure à 8000 Da dans une composition d'héparine extraite d'un animal marin vascularisé non mammalien.

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