C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/06 (2006.01) C07D 223/00 (2006.01) C07D 307/00 (2006.01)
Patent
CA 2479394
The invention relates to industrial scale-executable methods for producing norgalanthamine, norgalanthamine derivatives and their isomers of general formula (A) as well as their salts or hydrates of general formula (B). An oxidative demethylation and a catalytic demethylation of the corresponding galanthamine compounds serve as methods for producing the compounds of general formula (A) or (B).
L'invention concerne des procédés exécutables à l'échelle industrielle pour la production de norgalanthamine, de dérivés de norgalanthamine et de leurs isomères de formule générale (A), ainsi que de leurs sels ou hydrates de formule générale (B). On utilise comme procédés pour produire les composés de formule générale (A) ou (B) une déméthylation oxydante et une déméthylation catalytique des composés galanthamine correspondants.
Czollner Laszlo
Froehlich Johannes
Hirnschall Manfred
Jordis Ulrich
Kaelz Beate
Borden Ladner Gervais Llp
Sanochemia Pharmazeutika Aktiengesellschaft
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