Processes and intermediates for the preparation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 309/30 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2038259

18070 ABSTRACT OF THE DISCLOSURE The present invention is directed to a com- pound of structural formula (3): Image (3) which are intermediates useful for the preparation of 5-oxygenated derivatives of lovastatin and analogs at the 8-acyl side chain and 6-position of the polyhydro- naphtyl ring. Said derivatives of lovastatin and analogs thereof are useful for the treatment of hyper- cholesterolemia.

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