Production of thrombin inhibitors

Details Production of thrombin inhibitors Production of thrombin inhibitors

C - Chemistry, Metallurgy

12

N

195/1.2, 195/1.3

C12N 15/15 (2006.01) C07K 14/815 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1341496

A method for the production and secretion of proteins with hirudin activity in an eukaryotic host organism is provided. There are also provided hybrid vectors comprising a DNA sequence encoding a signal peptide upstream of and in reading frame with the structural gene for desulphatohirudin, and eukaryotic host organisms transformed with said hybrid vectors.

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