C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 38/17 (2006.01) A61K 38/45 (2006.01) C07K 14/47 (2006.01) C12N 9/12 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) C30B 29/58 (2006.01) G01N 33/53 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) G06F 17/50 (2006.01) A61K 38/00 (2006.01) G06F 19/00 (2006.01)
Patent
CA 2506246
The present invention relates to therapeutic compounds and methods of use of these therapeutic compounds for treating cellular proliferative disorders. The invention also provides three-dimensional structures of a Polo-like kinase and methods for designing or selecting small molecule inhibitors using these structures, and the therapeutic use of such compounds. The invention also includes a method for identifying novel phosphopeptide-binding domains.
La présente invention concerne des composés thérapeutiques et des procédés d'utilisation de ces composés pour le traitement de troubles à prolifération des cellules. L'invention concerne également, d'une part les structures tridimensionnelles d'une kinase ressemblant à une Polo, et des procédés pour concevoir ou sélectionner des inhibiteurs à petites molécules en utilisant ces structures, et d'autre part l'utilisation thérapeutique de ces composés. L'invention concerne enfin un procédé permettant d'identifier les domaines de liaison phosphopeptides de l'invention.
Cantley Lewis C.
Elia Andrew E. H.
Manke Isaac
Rellos Peter
Smerdon Stephen J.
Beth Israel Deaconess Medical Center
Massachusetts Institute Of Technology
Medical Research Council
Smart & Biggar
LandOfFree
Products and processes for modulating peptide-peptide... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Products and processes for modulating peptide-peptide..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Products and processes for modulating peptide-peptide... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1378741