C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/48 (2006.01) A61K 31/7088 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61K 48/00 (2006.01) A61P 31/18 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) C07K 14/47 (2006.01) C07K 16/10 (2006.01) C12Q 1/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2468326
The present invention relates to protein-protein interactions involved in AIDS. More specifically, the present invention relates to complexes of polypeptides or polynucleotides encoding the polypeptides, fragments of the polypeptides, antibodies to the complexes, selected Interacting Domains (SID®) which are identified due to the protein-protein interactions, methods for screening drugs of agents which modulate the interaction of proteins and pharmaceutical compositions that are capable of modulating the protein-protein interactions.
La présente invention concerne des interactions entre protéines participant du sida. L'invention concerne plus particulièrement des complexes de polypeptides ou de polynucléotides codant les polypeptides, des fragments des polypeptides, des anticorps de ces complexes des domaines d'interaction sélectionnés ou SID® (Selected Interacting Domains) identifiés de par les interactions entre protéines, des procédés de recherche systématique d'agents modulateurs de l'interaction entre protéines, et des compositions pharmaceutiques capables de moduler ces interactions entre protéines.
Benarous Richard
Berlioz-Torrent Clarisse
Blot Guillaume
Emiliani Stephane
Legrain Pierre
Goudreau Gage Dubuc
Hybrigenics
Laboratoire Biodim
LandOfFree
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