Proteins, polynucleotides encoding them and methods of using...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2440219

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention porte sur des séquences d'acide nucléique qui codent de nouveaux polypeptides. L'invention porte également sur des polypeptides codés par ces séquences d'acide nucléique et sur des anticorps qui se lient de manière immunospécifique à ce polypeptide, ainsi que sur des dérivés, des variants, des mutants ou des fragments du polypeptide, du polynucléotide ou de l'anticorps précités. L'invention porte également sur des procédés thérapeutiques, diagnostiques et de recherche de diagnostic, de traitement et de prévention de troubles dans lesquels interviennent l'un quelconque de ces nouveaux acides nucléiques humains et de ces nouvelles protéines humaines.

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