Proteins, polynucleotides encoding them and methods of using...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2430634

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention porte: sur des séquences d'acides nucléiques, codant pour de nouveaux polypeptides; sur les polypeptides codés par lesdites séquences et des anticorps se fixant immunospécifiquement auxdits polypeptides, et sur des dérivés, variantes, mutants ou fragments desdits polypeptides, polynucléotides, ou anticorps. L'invention porte en outre sur des procédés thérapeutiques, diagnostiques et de recherche en vue du diagnostic, du traitement et de la prévention de troubles impliquant lesdits nouveaux acides nucléiques humains et les protéines associées.

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