Pumpcn compositions and uses thereof

Details Pumpcn compositions and uses thereof Pumpcn compositions and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 51/00 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 19/00 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/62 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574

Patent

CA 2423991

The present invention is directed to novel polypeptides Protein Upregulated in Metastatic Prostate Cancer (PUMPCn) and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

L'invention se rapporte à de nouveaux polypeptides de protéine régulée positivement dans le cancer de la prostate métastatique (PUMPCn) et à des molécules d'acide nucléique codant pour ces polypeptides. L'invention concerne en outre des vecteurs et des cellules hôtes comprenant ces séquences d'acide nucléique, des molécules polypeptidiques chimériques comprenant les polypeptides de l'invention, fusionnées à des séquences polypeptidiques hétérologues, des anticorps qui se lient aux polypeptides selon l'invention, ainsi que des procédés de production des polypeptides selon l'invention.

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