Purification of biologically-produced 1,3-propanediol

Details Purification of biologically-produced 1,3-propanediol Purification of biologically-produced 1,3-propanediol

C - Chemistry, Metallurgy

12

P

C12P 7/18 (2006.01) C07C 29/80 (2006.01) C07C 31/20 (2006.01)

Patent

CA 2522928

A process for purifying 1,3-propanediol from the fermentation broth of a cultured E. coli that has been bioengineered to synthesize 1,3-propanediol from sugar is provided. The basic process entails filtration, ion exchange and distillation of the fermentation broth product stream, preferably including chemical reduction of the product during the distillation procedure. Also provided are highly purified compositions of 1,3-propanediol.

La présente invention concerne un procédé permettant de purifier du 1,3-propanediol issu du bouillon de fermentation d'une culture de E. coli qui a été traité par génie biologique pour synthétiser le 1,3-propanediol à partir du sucre. Le procédé de base fait intervenir une filtration, un échange d'ions et une distillation du diluat du bouillon de fermentation, de préférence avec réduction chimique du produit pendant la distillation. L'invention concerne également des compositions hautement purifiées à base de 1,3-propanediol.

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