Purified immunoglobulin fusion proteins and methods of their...

Details Purified immunoglobulin fusion proteins and methods of their... Purified immunoglobulin fusion proteins and methods of their...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01) C07K 14/715 (2006.01) C07K 1/16 (2006.01) C07K 1/20 (2006.01)

Patent

CA 2717129

The invention provides methods and compositions for separating impurities during the manufacture of immunoglobulin (Ig) fusion proteins. Examples of impurities which may be removed in accordance with the methods of the invention include inactive forms of the Ig fusion protein and/or aggregates.

Linvention concerne des procédés et des compositions pour séparer des impuretés lors de la fabrication de protéines hybrides dimmunoglobuline (Ig). Des exemples dimpuretés qui peuvent être éliminées conformément aux procédés de linvention comprennent des formes inactives de la protéine hybride dIG et/ou des agrégats.

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