Purine derivatives further comprising a mercapto-acylamino...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/30 (2006.01) A61K 31/522 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2723922

Substituted heterocycles of the general formula (I) with the residues A, R1, R2 and R3 as explained in detail in the description are described. The compounds are suitable in particular as neutral endopeptidase inhibitors and are highly potent.

La présente invention concerne des hétérocycles substitués de formule générale (I) dans laquelle les résidus A, R1, R2 et R3 sont tels qu'expliqués en détail dans la description. Les composés sont appropriés, en particulier, comme inhibiteurs de l'endopeptidase neutre et sont très puissants.

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