Pyrazinone derivatives as insulin secretion stimulators,...

Details Pyrazinone derivatives as insulin secretion stimulators,... Pyrazinone derivatives as insulin secretion stimulators,...

C - Chemistry, Metallurgy

07

D

C07D 241/18 (2006.01) A61K 31/4965 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2717753

The present invention relates to pyrazi-none derivatives of formula (I), wherein n, R1, R2, R3 and R4 are as defined in claim 1, as insulin secretion stimulators. The invention also relates to the prepara-tion and use of these pyrazinone derivatives for the prophylaxis and/or treatment of diabetes and patholo-gies associated.

La présente invention concerne des dérivés de pyrazinone de la formule (I), dans laquelle n, R1, R2, R3 et R4 sont tels que définis dans la revendication 1, comme stimulateurs de la sécrétion dinsuline. Linvention concerne également la préparation et lutilisation de ces dérivés de pyrazinone pour la prophylaxie et/ou le traitement du diabète et des pathologies associées.

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