Pyrazoles useful in the treatment of inflammation

Details Pyrazoles useful in the treatment of inflammation Pyrazoles useful in the treatment of inflammation

C - Chemistry, Metallurgy

07

D

C07D 231/16 (2006.01) A61K 31/415 (2006.01) A61P 29/00 (2006.01) C07D 231/12 (2006.01) C07D 231/14 (2006.01)

Patent

CA 2626358

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

L'invention concerne des composés représentés par la formule (I), dans laquelle R1, R2, X1, X2 et n ont les notations données dans le descriptif, et des sels pharmaceutiquement acceptables de ces composés. Lesdits composés sont utiles pour traiter des maladies dans lesquelles une inhibition de l'activité d'une lipoxygénase (p. ex. la lipoxygénase 15) est souhaitée et/ou requise, et en particulier dans le traitement de l'inflammation.

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