C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/208, 260/280
C07D 231/06 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 409/06 (2006.01)
Patent
CA 1311760
ABSTRACT OF THE DISCLOSURE This invention relates to new 2-pyrazoline derivatives represented by the following general formula (A): Image (A) ( wherein R1 denotes a pyridyl, a pyrazyl or an alkoxyl group; and R2 stands for hydrogen atom, an alkyl, a pyridyl, a furyl, phenyl or a substituted phenyl group ), and to a process for producing the same. This invention also relates to agents for treating cerebrovascular diseases containing, as active ingredients, a 2-pyrazoline derivative represented by the following general formula (G): Image (G) ( wherein R3 denotes hydrogen atom, an alkyl, acetyl, an alkoxycarbonyl, an amino, benzoyl, a substituted benzoyl, a pyridylcarbonyl, a furylcabonyl, a thienylcarbonyl, a pyrazylcarbonyl, an N-substituted carbamoyl, an N-sub- stituted thiocarbamoyl, or carboxyl group; and R4 stands for hydrogen atom, an alkyl, a pyridyl, a thienyl, a furyl, cyclohexyl, phenyl or a substituted phenyl group ) or a pharmaceutically acceptable salt thereof.
569357
Iizuka Hajime
Kawazura Hiroshi
Namekawa Hiroshi
Odate Makoto
Shiga Yoshio
Mitsui Chemicals Incorporated
Ridout & Maybee Llp
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