Pyrazolopyridines and analogs thereof

Details Pyrazolopyridines and analogs thereof Pyrazolopyridines and analogs thereof

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61K 31/4745 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2602800

Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4- amines, 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, and prodrugs thereof, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.

Pyrazolopyridine-4-amines, pyrazoloquinoline-4-amines, pyrazolonaphtyridine-4-amines, 6,7,8,9-tétrahydropyrazoloquinoline-4-amines, et promédicaments correspondants, compositions pharmaceutiques les contenant, intermédiaires, procédés d'élaboration et, enfin, procédés relatifs à l'utilisation des composés considérés, à la fois comme immunomodulateurs, permettant d'induire ou d'inhiber la biosynthèse des cytokines chez l'animal, et pour le traitement des maladies, y compris les maladies virales et néoplasiques.

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