Pyridazin-3 (2h) -one derivatives and their use as pde4...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 237/22 (2006.01) A61K 31/50 (2006.01) A61K 31/501 (2006.01) A61P 11/06 (2006.01) C07D 237/24 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2545193

New pyridazin-e-(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.

L'invention concerne de nouveaux dérivés de pyridazine-3(2H)-ones dont la structure chimique est représentée par la formule (I), ainsi que des procédés de fabrication de ces dérivés, des compositions pharmaceutiques contenant ces dérivés, et leur utilisation thérapeutique en tant qu'inhibiteurs de phosphodiesterase 4.

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