Pyridine and pyrimidine derivatives as inhibitors of histone...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/42 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 213/82 (2006.01) C07D 409/10 (2006.01)

Patent

CA 2631874

This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.

Cette invention concerne de nouveaux composés de formule (I) dans laquelle R1, R2, R3, R4, R5, R6, R7, R8, R9 et X ont les correspondances indiquées, ces composés ayant une activité enzymatique d'inhibition d'histone désacétylase, leur préparation, des compositions les contenant, et leur utilisation en tant que médicament.

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