C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/44 (2006.01) A61K 31/4425 (2006.01) A61P 35/00 (2006.01) C07D 213/75 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2589773
The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula (I): (A chemical formula should be inserted here - please see paper copy enclosed herewith) (I) which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
La présente invention concerne des composés chimiques, ou des sels de qualité pharmaceutique de ces composés, de formule (I) : (Une formule chimique doit être insérée ici - se reporter à la copie papier incluse) (I). Lesdits composés et leurs sels présentent une activité inhibitrice vis-à-vis de B Raf et peuvent donc être employés pour leur activité anticancéreuse dans des méthodes de traitement de l'organisme humain ou animal. La présente invention concerne également des procédés d'élaboration desdits composés chimiques, des préparations pharmaceutiques les contenant ainsi que leur emploi dans l'élaboration de médicaments pouvant être utilisés pour obtenir un effet anticancéreux chez un animal à sang chaud tel que l'homme.
Almeida Lynsie
Aquila Brian
Cook Donald
Cowen Scott
Dakin Les
Astrazeneca Ab
Fetherstonhaugh & Co.
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