C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/078 (2006.01) A61K 38/05 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2604967
The invention relates to 4-aminocarbonyl-pyrimidine derivatives and their use as P2Y12 receptor antagonists in the treatment and/or prevention and/or treatment of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals. Formule (I).
L'invention concerne des dérivés de 4-aminocarbonyl-pyrimidine et leur utilisation en tant qu'antagonistes du récepteur dans le traitement et/ou la prévention de maladies ou de manifestations périphériques vasculaires, viscérales, hépatique et rénales vasculaires et cardio-vasculaires ou cérébrovasculaires associées à l'agrégation plaquettaire, dont la thrombose chez les humains et autres mammifères. Formule (I).
Caroff Eva
Fretz Heinz
Hilpert Kurt
Houille Olivier
Hubler Francis
Actelion Pharmaceuticals Ltd
Gowling Lafleur Henderson Llp
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