Pyrimidine derivatives and their use as p2y12 receptor...

Details Pyrimidine derivatives and their use as p2y12 receptor... Pyrimidine derivatives and their use as p2y12 receptor...

C - Chemistry, Metallurgy

07

K

C07K 5/078 (2006.01) A61K 38/05 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2604967

The invention relates to 4-aminocarbonyl-pyrimidine derivatives and their use as P2Y12 receptor antagonists in the treatment and/or prevention and/or treatment of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals. Formule (I).

L'invention concerne des dérivés de 4-aminocarbonyl-pyrimidine et leur utilisation en tant qu'antagonistes du récepteur dans le traitement et/ou la prévention de maladies ou de manifestations périphériques vasculaires, viscérales, hépatique et rénales vasculaires et cardio-vasculaires ou cérébrovasculaires associées à l'agrégation plaquettaire, dont la thrombose chez les humains et autres mammifères. Formule (I).

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