C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 239/48 (2006.01) C07D 239/50 (2006.01) C07D 239/80 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 451/04 (2006.01) C07D 451/06 (2006.01) C07D 471/10 (2006.01) C07D 487/04 (2006.01) C07D 487/10 (2006.01) C07D 5
Patent
CA 2463989
The invention concerns tri-substituted pyrimidines of formula (I), wherein Ra to Re are such as defined in the description, said compounds being used for treating diseases characterized by excessive or abnormal cell proliferation. The invention also concerns the use of said compounds for making a pharmaceutical agent exhibiting said properties, as well as methods for making said compounds.
La présente invention concerne des pyrimidines à substitution triple de la formule (I) dans laquelle R¿a? à R¿e? ont la signification donnée dans le descriptif, lesdits composés servant au traitement de maladies caractérisées par une prolifération cellulaire excessive ou anormale. L'invention concerne également l'utilisation desdits composés dans la fabrication d'un agent pharmaceutique présentant les propriétés citées auparavant, ainsi que des procédés de fabrication desdits composés.
Dahmann Georg
Himmelsbach Frank
Krist Bernd
Lenter Martin
Pautsch Alexander
Boehringer Ingelheim International Gmbh
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Boehringer Ingelheim Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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