C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01) C07D 231/56 (2006.01) C07D 235/08 (2006.01) C07D 239/30 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2432000
Pyrimidine derivatives of formula: (see formula I) and salts, solvates, pharmaceutically acceptable esters or amides thereof, are useful as VEGFR2 inhibitors; the described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
L'invention concerne des dérivés pyrimidine utilisés comme inhibiteurs de VEGFR2. L'invention concerne également des méthodes de production de ces dérivés ainsi que des méthodes utilisant lesdits dérivés pour traiter des maladies hyperprolifératives.
Boloor Amogh
Cheung Mui
Davis Ronda
Harris Philip Anthony
Hinkle Kevin
Glaxo Group Limited
Glaxosmithkline Llc
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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