Pyrrolidine-2-ones as factor xa inhibitors

Details Pyrrolidine-2-ones as factor xa inhibitors Pyrrolidine-2-ones as factor xa inhibitors

C - Chemistry, Metallurgy

07

D

C07D 207/273 (2006.01) A61K 31/40 (2006.01) C07D 207/26 (2006.01) C07D 401/12 (2006.01) C07D 403/10 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/10 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2471461

The invention relates to compounds of formula (I): , and pharmaceutically acceptable derivatives thereof. The invention also relates to processes for the preparation of compounds of formula (I), pharmaceutical compositions containing compounds of formula (I) and to the use of compounds of formula (I) in medicine, particularly in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.

L'invention concerne des composés de formule (I) ainsi que des dérivés pharmaceutiquement acceptables desdits composés. L'invention concerne également des procédés de préparation des composés de formule (I), des compositions pharmaceutiques contenant ces composés de formule (I), ainsi que l'utilisation des composés de formule (I) en médecine, notamment en vue d'améliorer un état clinique pour lequel un inhibiteur du facteur Xa est indiqué.

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