C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/34 (2006.01) A61K 31/381 (2006.01) A61K 31/519 (2006.01) C07H 19/14 (2006.01)
Patent
CA 2381297
Compositions and methods for pyrrolo[2,3-d]pyrimidine nucleoside analogs having substituents at the C4' and C5' positions of the ribofuranose moiety are presented. Contemplated compositions exhibit, among other things, anti- cancer and immunomodulating effects at reduced cytotoxicity.
La présente invention concerne des compositions et des techniques destinées à des analogues nucléosidiques de pyrrolo[2,3-d]pyrimidine possédant des substituants en C4' et C5' de la fraction de ribofuranose. Ces compositions présentent, entre autres effets, des effets anticancéreux et immunorégulateurs pour une cytotoxicité réduite.
Gunic Esmir
Pietrzkowski Zbigniew
Tam Robert
Wang Guangyi
Icn Pharmaceuticals Inc.
Ribapharm Inc.
Smart & Biggar
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