Pyrrolo¬2,3-d|pyrimidine nucleoside analogs

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 487/04 (2006.01) A61K 31/34 (2006.01) A61K 31/381 (2006.01) A61K 31/519 (2006.01) C07H 19/14 (2006.01)

Patent

CA 2381297

Compositions and methods for pyrrolo[2,3-d]pyrimidine nucleoside analogs having substituents at the C4' and C5' positions of the ribofuranose moiety are presented. Contemplated compositions exhibit, among other things, anti- cancer and immunomodulating effects at reduced cytotoxicity.

La présente invention concerne des compositions et des techniques destinées à des analogues nucléosidiques de pyrrolo[2,3-d]pyrimidine possédant des substituants en C4' et C5' de la fraction de ribofuranose. Ces compositions présentent, entre autres effets, des effets anticancéreux et immunorégulateurs pour une cytotoxicité réduite.

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