Pyrrolopyridines as kinase inhibitors

Details Pyrrolopyridines as kinase inhibitors Pyrrolopyridines as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/497 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2724262

Compounds of Formula (I) are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Des composés de formule (I) sont utiles pour linhibition de CHK1 et/ou CHK2. Des procédés dutilisation des composés de formule (I) et de stéréoisomères et de leurs sels pharmaceutiquement acceptables, pour diagnostic, prévention ou traitement in vitro, in situ et in vivo de tels troubles dans des cellules mammifères ou des affections pathologiques associées sont décrits.

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