Pyrrolyl tetrahydrobenzoquinoxaline diones, their...

Details Pyrrolyl tetrahydrobenzoquinoxaline diones, their... Pyrrolyl tetrahydrobenzoquinoxaline diones, their...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/495 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2201527

Pyrrolyl-tetrahydrobenzoquinoxaline diones having the formula (I) are disclosed, as well as their tautomeric and isomeric forms, their physiologically compatible salts and their preparation. In the formula, the variables have the meanings given in the description. These new compounds are glutamate antagonists useful in the therapy of neurodegenerative diseases.

L'invention concerne des pyrrolyltétrahydrobenzoquinoxalindiones répondant à la formule (I), leurs formes tautomères et isomères, leurs sels physiologiquement compatibles et leur préparation. Les variables de ladite formule ont la signification donnée dans la description. Ces nouveaux composés sont des antagonistes du glutamate utiles comme agents thérapeutiques pour le traitement de maladies neurodégénératives.

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