Quantitative and qualitative in vivo tissue examination...

A - Human Necessities – 61 – B

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A61B 10/00 (2006.01) A61B 5/00 (2006.01)

Patent

CA 2158640

A system for examination of biological tissue of a subject (10) includes a light source (14), (16), a light detector (22), a gated integrator (26), (28), and an integrator timing control (19) adapted to integrate detected photons over at least two selected time intervals. The light source (14), (16) is adapted to introduce into the tissue, at an input port, pulses of electromagnetic radiation of a selected wavelength in the visible or infrared range. The detector (22) detects photons of modified pulses that have migrated in the tissue from the input port. The integrator (26), (28) registers all photons detected over preselected time intervals of the arrival time of the modified pulses. A processor (30) adapted to receive data from the integrator (26), (28) determines a physiological property of the examined tissue based on the number of photons integrated over each time interval.

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