Quaternary ammonium compounds having muscle relaxation activity

Details Quaternary ammonium compounds having muscle relaxation activity Quaternary ammonium compounds having muscle relaxation activity

C - Chemistry, Metallurgy

07

C

260/593, 260/585

C07C 211/63 (2006.01) A61K 31/14 (2006.01) A61K 31/245 (2006.01) C07C 43/174 (2006.01) C07C 45/41 (2006.01) C07C 69/612 (2006.01) C07C 69/618 (2006.01) C07C 205/11 (2006.01) C07C 211/27 (2006.01) C07C 211/28 (2006.01) C07C 211/29 (2006.01) C07C 211/30 (2006.01) C07C 211/49 (2006.01) C07C 215/18 (2006.01) C07C 215/30 (2006.01) C07C 215/40 (2006.01) C07C 217/10 (2006.01) C07C 217/20 (2006.01) C07C 217/48 (2006.01) C07C 219/22 (2006.01) C07C 225/06 (2006.01) C07C 229/34 (2006.01) C07C 229/38 (2006.01) C07C 233

Patent

CA 2013432

ABSTRACT OF THE DISCLOSURE A guaternary ammonium compound having a muscle relaxation activity represented by the formula (I): Image wherein R1 represents a methylene, a lower alkylenoxy, a lower alkenylene, a lower alkynylene, -CO-, -COO-, a lower alkylene carbonyloxy, -CH(OR5)-, a lower alkylenecarbonyl, a hydroxy lower alkylene, -O-, -S-, -SO-, or -SO2-; R2 represents a hydrogen atom, a hydroxy lower alkyl, an aldehyde, a lower alkyl carbonyl, -NO2 , or -NHR6; R3 represents a hydrogen atom of a group -R1,(CH2)a-[CH(CH2A)-CH2]b-A; R4 represents an anion; R5 and R6 represent a hydrogen atom or a acetyl; A represents a quaternary ammonium group; a represents an integer of 1 to 8; b represents 0 or 1; m represents an integer of 1 to 4; and (Z) represents a trivalent benzene ring, a trivalent naphthalene ring, a trivalent diphenyl or a trivalent ethane radical.

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