Quaternization of the additive aminoalkyl methacrylate...

Details Quaternization of the additive aminoalkyl methacrylate... Quaternization of the additive aminoalkyl methacrylate...

A - Human Necessities

61

K

A61K 47/00 (2006.01) A61L 15/44 (2006.01) B01F 17/00 (2006.01) C08L 33/08 (2006.01) C08L 101/00 (2006.01)

Patent

CA 2708431

The present invention relates to a strategy for improving the permeability and solubility of pharmaceuticals, based on adding a chemically modified amino alkyl methacrylate copolymer E, wherein the chemical modification is the quarternization of a fraction of the existing amino alkyl groups.

L'invention concerne une stratégie d'amélioration de la perméabilité et de la solubilité de substances pharmaceutiques qui se fonde sur l'addition d'un méthacrylate d'aminoalkyle copolymère E chimiquement modifié, sachant que la modification chimique consiste en la quaternisation d'une part des groupes aminoalkyle présents.

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