Quinazolines for pdk1 inhibition

Details Quinazolines for pdk1 inhibition Quinazolines for pdk1 inhibition

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2648529

The invention provides quinazoline compounds that are inhibitors of PDKl. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

La présente invention concerne de nouveaux composés de quinazoline qui sont des inhibiteurs de PDK1. L'invention a également trait à des compositions pharmaceutiques comprenant ces composés ainsi qu'à des procédés de traitement des maladies prolifératives, telles que les cancers, par lesdits composés ou compositions.

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