Quinoline derivative or salt thereof and remedy for cardiac...

Details Quinoline derivative or salt thereof and remedy for cardiac... Quinoline derivative or salt thereof and remedy for cardiac...

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2134448

ABSTRACT OF DISCLOSURE A quinoline derivative represented by general formula (1), a medicinally acceptable salt thereof, and a remedy for cardiac diseases containing the same: Image (1) [wherein ring A represents a furan, dihydrofuran or dioxolane ring, and R1 represents an aminoalkyl group]. The compound (1) has a positively inotropic effect on myocardia and an antiarrhythmic effect, and can dilate blood vessels without extremely increasing the heart rate. Therefore, a remedy for cardiac diseases containing the same as the active ingredient is remarkably useful for treating cardiac insufficiency, arrhythmia, and so forth. - 358 -

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