Quinone-based therapeutic agent for hepatopathy

Details Quinone-based therapeutic agent for hepatopathy Quinone-based therapeutic agent for hepatopathy

A - Human Necessities

61

K

A61K 31/122 (2006.01) A61P 1/16 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2488880

To provide a remedy for a liver disease particularly by inhibiting the onset of portal-vein infusion (PVI), an excellent remedy/preventive for a liver disease containing menatetrenone as the active ingredient is disclosed. This remedy/preventive for a liver disease is efficacious against liver cancer, in particular, DCP (des-.gamma.-carboxy prothrombin)-positive liver cancer. The above-described remedy/preventive for a liver disease containing menatetrenone as the active ingredient exerts a remarkable effect of improving the prognosis following a therapy for liver cancer, thereby showing an excellent effect as a liver cancer recurrence inhibitor too.

Afin d'obtenir un remède contre une hépatopathie notamment par inhibition du début d'une perfusion veine-porte (PVI), l'invention concerne un excellent remède/préventif contre une hépatopathie contenant en tant que principe actif la menatetrènone. Ce remède/préventif contre une hépatopathie est efficace contre le cancer du foie, en particulier, le cancer du foie positif à DCP (des-.gamma.-carboxyprothrombine). Le remède/préventif ci-dessus décrit contre une hépatopathie contenant de la menatetrènone en tant que principe actif exerce un effet remarquable améliorant le pronostic suivant une thérapie du cancer du foie, présentant ainsi également un excellent effet en tant qu'inhibiteur de récurrence de cancer du foie.

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