Radio-immuno assay for hepatitis b virus pres 2 antibodies

G - Physics – 01 – N

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167/44

G01N 33/545 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2022343

7740P/5514A 17954 TITLE OF THE INVENTION A RADIO-IMMUNO ASSAY FOR HEPATITIS B VIRUS PreS2 ANTBIODIES ABSTRACT OF THE DISCLOSURE Anti-hepatitis B virus surface protein (anti-HBS) antibody is adsorbed onto the surface of a substratum. Hepatitis B virus PreS2+S (PreS2+S) protein is then adsorbed onto the same surface through the interaction of the anti-HBS antibody with the "S" portion of the PreS2+S protein. The coated surface is then incubated concomitantly with the test sample and a radiolabelled antibody specific for the "PreS2" portion of the PreS2+S protein.

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