Radiopharmaceutical products for selective marking of...

C - Chemistry – Metallurgy – 07 – F

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C07F 13/00 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 2309795

L'invention concerne des produits radiopharmaceutiques utiles pour le marquage sélectif des lymphones comprenant un complexe d'un métal de formule : [M(R1CS2)(R1CS3)2] dans laquelle M est choisi parmi 99m Tc, 186Re et 188Re, et R1 représente un groupe alkyle, cycloalkyle, aralkyle ou aryle, éventuellement substitué, obtenus par réaction d'un pertechnétate ou d'un perrhénate avec un réducteur tel que SnCl2ZP2O en présence d'un dithiocarboxylate de formule : (R1CS2)-Z2+.

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