Rankl antibody-pth/pthrp chimeric molecules

Details Rankl antibody-pth/pthrp chimeric molecules Rankl antibody-pth/pthrp chimeric molecules

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) A61P 19/10 (2006.01) C07K 14/635 (2006.01) C07K 14/705 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2628628

Chimeric molecules comprising receptor activator of NF-kB ligand (RANKL) antibodies and parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) peptides are described. Compositions and methods for the treatment of bone diseases are also described.

La présente invention concerne des molécules chimères comprenant un activateur du récepteur d~un anticorps du ligand NF-kB (RANKL) et des peptides de l~hormone parathyroïdienne/de la protéine apparentée à l~hormone parathyroïdienne (PTH/PTHrP). Des compositions et procédés pour le traitement de maladies osseuses sont également décrits.

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