Rate controlling membranes for controlled drug delivery devices

Details Rate controlling membranes for controlled drug delivery devices Rate controlling membranes for controlled drug delivery devices

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 9/00 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2315890

This invention provides rate controlling membranes for controlled drug delivery devices that are stable over time and exhibit more predictable and consistent membrane functionality. According to another aspect, the membranes have enhanced permeability. According to the invention, the rate controlling membrane of a controlled drug delivery device is subjected to a pre-treatment annealing process wherein it is subjected to an elevated temperature for a predetermined time period and subsequently cooled to ambient conditions before incorporation into a controlled drug delivery device.

Membranes de régulation de débit pour dispositifs d'administration régulée de médicaments, qui restent stables avec le temps et qui présentent une fonctionnalité plus prévisible et plus régulière. Selon un autre aspect, lesdites membranes présentent une perméabilité améliorée. Selon la présente invention, lesdites membranes sont soumises à titre de pré-traitement à un processus de recuit lors duquel elles sont soumises à une température élevée pendant une durée prédéterminée, puis refroidies à la température ambiante, avant d'être incorporées dans des dispositifs d'administration régulée de médicaments.

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