A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/39 (2006.01) A61K 47/30 (2006.01) A61K 47/36 (2006.01) A61P 17/02 (2006.01) C07K 14/78 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2321177
The invention provides an extracellular matrix for enhancing wound healing. The extracellular matrix comprises a recombinant fibronectin protein and a backbone matrix, wherein the recombinant fibronectin protein comprises peptides from two or more fibronectin domains. The extracellular matrix facilitates wound healing by providing hemostasis and, in addition, an environment that intrinsically recruits new tissue cells to the wound site. The extracellular matrix according to the subject invention is thus used in a method for enhancing wound healing. The method comprises applying the extracellular matrix to the wound.
L'invention porte sur une matrice extracellulaire destinée à accélérer la cicatrisation des blessures et comprenant une protéine de fibronectine de recombinaison et une matrice de squelette, cette protéine de fibronectine de recombinaison comprenant des peptides provenant d'au moins deux domaines de fibronectine. La matrice extracellulaire de l'invention accélère la cicatrisation des blessures par hémostase, et de plus, dans un environnement qui recrute intrinsèquement de nouvelles cellules tissulaires sur le site de la blessure. La matrice extracellulaire peut donc être utilisée pour accélérer la cicatrisation des blessures. Le procédé consiste à appliquer cette matrice extracellulaire sur une blessure.
Clark Richard A.
Gailit James
Greiling Doris
Gowling Lafleur Henderson Llp
The Research Foundation Of State University Of New York
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