C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/525 (2006.01) C07K 14/715 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2452245
The invention relates to recombinant fusion proteins having the property of being able to form trimers. Said recombinant fusion proteins comprise at least one component A and at least one component B. Component B . Component B has trimerizing properties and component A has biological properties. The invention also relates to trimers of said recombinant fusion proteins. The invention further relates to the use of said trimers in the production of a medicament or the use thereof for in-vitro diagnosis or in the production of in-vitro diagnosis agent. The invention also relates to DNA sequences coding for said fusion protein and expression vectors and host cells containing said DNA sequences or expression vector.
L'invention concerne des protéines hybrides recombinées possédant la propriété de pouvoir former des trimères. Ces protéines hybrides recombinées présentent au moins un composant A possédant des propriétés biologiques et au moins un composant B possédant la propriété de former des trimères. L'invention concerne également des trimères de ces protéines hybrides recombinées, ainsi que l'utilisation de ces trimères pour produire un médicament ou pour établir un diagnostic in vitro ou encore pour produire un agent de diagnostic in vitro. L'invention concerne en outre des séquences d'ADN qui codent pour une telle protéine hybride, ainsi que des vecteurs d'expression et des cellules hôtes qui contiennent cette séquence d'ADN ou ce vecteur d'expression.
Schneider Pascal
Tschopp Juerg
Apoxis Sa
Ridout & Maybee Llp
LandOfFree
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