Recombinant hk2 polypeptide

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/57 (2006.01) C07K 16/40 (2006.01) C12N 5/20 (2006.01) C12N 9/64 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2189774

An isolated. substantially homogenous hK2 polypeptide is provided as well as isolated nucleic acid molecules encoding hK2 polypeptide, including (a) a cDNA molecule comprising the nucleotide sequence of the coding region of human hK2 gene, (b) a DNA molecule capable of hybridizing under stringent conditions to a molecule of (a); and (c) a genetic variant of any of the DNA molecules of (a) and (b) which encodes of polypeptide processing an antigenic function of naturally occurring polypeptide.

Polypeptide hK2 isolé, sensiblement homogène, et molécules d'acide nucléique isolées codant le polypeptide hK2, notamment (a) une molécule d'ADNc comprenant la séquence de nucléotides de la région codante du gène hK2 humain; (b) une molécule d'ADN capable d'hybridation dans des conditions strictes avec une molécule de (a); et (c) une variante génétique de l'une quelconque des molécules d'ADN (a) et (b), qui code le polypeptide assurant une fonction antigénique du polypeptide naturel.

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