F - Mech Eng,Light,Heat,Weapons – 15 – D
Patent
F - Mech Eng,Light,Heat,Weapons
15
D
F15D 1/02 (2006.01) F04B 19/00 (2006.01) G01N 33/50 (2006.01) G01N 37/00 (2006.01)
Patent
CA 2471686
A method of transporting a desired fluid in a channel includes: providing a working fluid to transport the desired fluid, such as a sample; providing a first segment of a first buffer fluid which is immiscible with the working fluid and the desired fluid; providing a first segment of the desired fluid; providing a second segment of a second buffer fluid which is immiscible with the working fluid and the desired fluid; providing the desired fluid to be transported and further manipulated; and transporting the desired fluid in the channel by applying a motive force to the working fluid which in turn exerts force against the desired fluid through the first and second buffer fluid. The method prevents dilution of a sample in an apparatus such as a diagnostic analyzer or an apparatus for immunohematological testing of blood. A microfluidics handling system includes a microsystem platform that has: a substrate having: a first flat, planar surface; and a second flat planar surface opposite to the first surface. The first surface includes: at least one microchannel; an optional reagent source; an optional reaction chamber; a source of motive force to transport the fluid; a working fluid in the microchannels; a first segment of a first buffer fluid which is immiscible with the working fluid and the desired fluid; a first segment of the desired fluid; a second segment of a second buffer fluid which is immiscible with the working fluid and the desired fluid; and the desired fluid to be transported and further manipulated, wherein the fluid is present in the microchannels in the order of working fluid; first buffer fluid; first segment of the desired fluid, second buffer fluid; and the desired fluid.
Ding Zhong
Jacobs Merrit
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Ortho-Clinical Diagnostics Inc.
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